PAGE 1 000 A000000 01/31/2014 000 C000000 0001216583 000 D000000 N 000 E000000 NF 000 F000000 Y 000 G000000 N 000 H000000 N 000 I000000 6.1 000 J000000 A 001 A000000 NUVEEN PREFERRED INCOME OPPORTUNITIES FUND 001 B000000 811-21293 001 C000000 3129178200 002 A000000 333 WEST WACKER DRIVE 002 B000000 CHICAGO 002 C000000 IL 002 D010000 60606 002 D020000 1286 003 000000 N 004 000000 N 005 000000 N 006 000000 N 007 A000000 N 007 B000000 0 007 C010100 1 008 A000001 NUVEEN FUND ADVISORS, LLC 008 B000001 A 008 C000001 801-14147 008 D010001 CHICAGO 008 D020001 IL 008 D030001 60606 008 D040001 1286 008 A000002 NWQ INVESTMENT MANAGEMENT COMPANY, LLC 008 B000002 S 008 C000002 801-61379 008 D010002 LOS ANGELES 008 D020002 CA 008 D030002 90067 008 A000003 NUVEEN ASSET MANAGEMENT, LLC 008 B000003 S 008 C000003 801-71957 008 D010003 CHICAGO. 008 D020003 IL 008 D030003 60606 008 D040003 1286 012 A000001 COMPUTERSHARE 012 B000001 84-05925 012 C010001 PROVIDENCE 012 C020001 RI 012 C030001 02940 013 A000001 ERNST & YOUNG LLP 013 B010001 CHICAGO PAGE 2 013 B020001 IL 013 B030001 60606 014 A000001 NUVEEN INVESTMENTS, LLC 014 B000001 8-13464 015 A000001 STATE STREET BANK AND TRUST COMPANY 015 B000001 C 015 C010001 BOSTON 015 C020001 MA 015 C030001 02110 015 E010001 X 018 000000 Y 019 A000000 Y 019 B000000 209 019 C000000 NUVEENFUND 020 A000001 RAYMOND JAMES 020 B000001 59-1237041 020 C000001 22 020 A000002 CREDIT SUISSE 020 B000002 13-5659485 020 C000002 13 020 A000003 SIDOTI & COMPANY LLC 020 B000003 36-4279615 020 C000003 11 020 A000004 ROBERT W. BAIRD 020 B000004 39-6037917 020 C000004 11 020 A000005 JP MORGAN CHASE 020 B000005 13-3224016 020 C000005 10 020 A000006 CITIGROUP 020 B000006 13-3214963 020 C000006 10 020 A000007 GUGGENHEIM CAPITAL 020 B000007 52-2144448 020 C000007 9 020 A000008 DEUTSCHE BANK 020 B000008 13-2730828 020 C000008 9 020 A000009 BARCLAYS CAPITAL 020 B000009 06-1031656 020 C000009 8 020 A000010 JEFFERIES & CO 020 B000010 95-2622900 020 C000010 8 021 000000 182 022 A000001 WELLS FARGO 022 B000001 41-1508325 022 C000001 18066 022 D000001 37444 022 A000002 JP MORGAN CHASE 022 B000002 13-3224016 PAGE 3 022 C000002 30047 022 D000002 23841 022 A000003 SUQSUEHANNA TRUST 022 B000003 23-6242866 022 C000003 29226 022 D000003 5663 022 A000004 HSBC 022 B000004 13-2650272 022 C000004 5285 022 D000004 24960 022 A000005 MORGAN STANLEY 022 B000005 13-2655998 022 C000005 25031 022 D000005 909 022 A000006 JEFFERIES & CO 022 B000006 95-2622900 022 C000006 4095 022 D000006 21668 022 A000007 CITIGROUP 022 B000007 13-3214963 022 C000007 10651 022 D000007 11145 022 A000008 BARCLAYS BANK PLC 022 B000008 13-4942190 022 C000008 10147 022 D000008 10710 022 A000009 CREDIT SUISSE 022 B000009 13-5659485 022 C000009 6064 022 D000009 12430 022 A000010 RBC DOMINION 022 B000010 13-5033225 022 C000010 5653 022 D000010 6613 023 C000000 253675 023 D000000 268275 024 000000 N 026 A000000 N 026 B000000 N 026 C000000 N 026 D000000 Y 026 E000000 N 026 F000000 N 026 G010000 N 026 G020000 N 026 H000000 N 027 000000 N 028 A010000 0 028 A020000 0 028 A030000 0 028 A040000 0 PAGE 4 028 B010000 0 028 B020000 0 028 B030000 0 028 B040000 0 028 C010000 0 028 C020000 0 028 C030000 0 028 C040000 0 028 D010000 0 028 D020000 0 028 D030000 0 028 D040000 0 028 E010000 0 028 E020000 0 028 E030000 0 028 E040000 0 028 F010000 0 028 F020000 0 028 F030000 0 028 F040000 0 028 G010000 0 028 G020000 0 028 G030000 0 028 G040000 0 028 H000000 0 030 A000000 0 030 B000000 0.00 030 C000000 0.00 031 A000000 0 031 B000000 0 032 000000 0 033 000000 0 035 000000 0 036 B000000 0 038 000000 0 042 A000000 0 042 B000000 0 042 C000000 0 042 D000000 0 042 E000000 0 042 F000000 0 042 G000000 0 042 H000000 0 043 000000 0 044 000000 0 045 000000 Y 046 000000 N 047 000000 N 048 000000 0.000 048 A010000 0 048 A020000 0.000 PAGE 5 048 B010000 0 048 B020000 0.000 048 C010000 0 048 C020000 0.000 048 D010000 0 048 D020000 0.000 048 E010000 0 048 E020000 0.000 048 F010000 0 048 F020000 0.000 048 G010000 0 048 G020000 0.000 048 H010000 0 048 H020000 0.000 048 I010000 0 048 I020000 0.000 048 J010000 0 048 J020000 0.000 048 K010000 0 048 K020000 0.000 049 000000 N 050 000000 N 051 000000 N 052 000000 Y 053 A000000 N 054 A000000 Y 054 B000000 N 054 C000000 N 054 D000000 N 054 E000000 N 054 F000000 N 054 G000000 N 054 H000000 Y 054 I000000 N 054 J000000 Y 054 K000000 N 054 L000000 N 054 M000000 Y 054 N000000 N 054 O000000 Y 055 A000000 N 055 B000000 N 056 000000 Y 057 000000 N 058 A000000 N 059 000000 Y 060 A000000 Y 060 B000000 Y 061 000000 0 062 A000000 N 062 B000000 0.0 PAGE 6 062 C000000 0.0 062 D000000 0.0 062 E000000 0.0 062 F000000 0.0 062 G000000 0.0 062 H000000 0.0 062 I000000 0.0 062 J000000 0.0 062 K000000 0.0 062 L000000 0.0 062 M000000 0.0 062 N000000 0.0 062 O000000 0.0 062 P000000 0.0 062 Q000000 0.0 062 R000000 0.0 063 A000000 0 063 B000000 0.0 066 A000000 Y 066 B000000 N 066 C000000 N 066 D000000 N 066 E000000 N 066 F000000 Y 066 G000000 N 067 000000 N 068 A000000 N 068 B000000 N 069 000000 N 070 A010000 Y 070 A020000 Y 070 B010000 Y 070 B020000 N 070 C010000 Y 070 C020000 N 070 D010000 Y 070 D020000 N 070 E010000 Y 070 E020000 N 070 F010000 Y 070 F020000 N 070 G010000 Y 070 G020000 N 070 H010000 Y 070 H020000 N 070 I010000 N 070 I020000 N 070 J010000 Y 070 J020000 Y 070 K010000 Y 070 K020000 Y PAGE 7 070 L010000 Y 070 L020000 Y 070 M010000 Y 070 M020000 N 070 N010000 Y 070 N020000 N 070 O010000 Y 070 O020000 N 070 P010000 N 070 P020000 N 070 Q010000 N 070 Q020000 N 070 R010000 Y 070 R020000 N 071 A000000 253675 071 B000000 268845 071 C000000 1343487 071 D000000 19 072 A000000 6 072 B000000 21639 072 C000000 25568 072 D000000 0 072 E000000 87 072 F000000 5694 072 G000000 0 072 H000000 0 072 I000000 3 072 J000000 117 072 K000000 36 072 L000000 73 072 M000000 19 072 N000000 0 072 O000000 0 072 P000000 2215 072 Q000000 0 072 R000000 13 072 S000000 28 072 T000000 0 072 U000000 0 072 V000000 0 072 W000000 72 072 X000000 8270 072 Y000000 0 072 Z000000 39024 072AA000000 0 072BB000000 4180 072CC010000 0 072CC020000 18628 072DD010000 36837 072DD020000 0 072EE000000 0 PAGE 8 073 A010000 0.3798 073 A020000 0.0000 073 B000000 0.0000 073 C000000 0.0000 074 A000000 0 074 B000000 22741 074 C000000 0 074 D000000 38544 074 E000000 666656 074 F000000 41475 074 G000000 0 074 H000000 0 074 I000000 599261 074 J000000 10880 074 K000000 0 074 L000000 9945 074 M000000 7048 074 N000000 1396550 074 O000000 9236 074 P000000 963 074 Q000000 0 074 R010000 0 074 R020000 0 074 R030000 0 074 R040000 411511 074 S000000 0 074 T000000 974840 074 U010000 96990 074 U020000 0 074 V010000 10.05 074 V020000 0.00 074 W000000 0.0000 074 X000000 141 074 Y000000 482804 075 A000000 0 075 B000000 965050 076 000000 8.99 077 A000000 N 078 000000 N 080 C000000 0 081 B000000 0 082 B000000 0 083 B000000 0 084 B000000 0 086 A010000 0 086 A020000 0 086 B010000 0 086 B020000 0 086 C010000 0 086 C020000 0 086 D010000 0 PAGE 9 086 D020000 0 086 E010000 0 086 E020000 0 086 F010000 0 086 F020000 0 087 A010000 COMMON STOCK 087 A020000 67073B106 087 A030000 JPC 088 A000000 N 088 B000000 N 088 C000000 N 088 D000000 Y SIGNATURE STEPHEN D. FOY TITLE VP & CONTROLLER