SECURITIES AND EXCHANGE COMMISSION
Washington, D.C.
20549
Form 6-K
Report of Foreign Private Issuer
Pursuant to Rule 13a-16 or 15d-16
of the Securities Exchange Act of 1934
For the month of November, 2006
Commission File Number 000-31062
Oncolytics Biotech Inc.
(Translation of registrants name into
English)
Suite 210, 1167 Kensington Crescent NW
Calgary, Alberta, Canada T2N 1X7
(Address of principal executive offices)
Indicate by check mark whether the registrant files or will file annual reports
under cover Form 20-F or Form 40-F.
Indicate by check mark if the registrant is submitting the Form 6-K in paper as
permitted by Regulation S-T Rule 101(b)(1): o
Note: Regulation S-T Rule 101(b)(1) only permits the submission in paper of a
Form 6-K if submitted solely to provide an attached annual report to security
holders.
Indicate by check mark if the registrant is submitting the Form 6-K in paper as
permitted by Regulation S-T Rule 101(b)(7): o
Note: Regulation S-T Rule 101(b)(7) only permits the submission in paper of a
Form 6-K if submitted to furnish a report or other document that the registrant
foreign private issuer must furnish and make public under the laws of the
jurisdiction in which the registrant is incorporated, domiciled or legally
organized (the registrants home country), or under the rules of the home
country exchange on which the registrants securities are traded, as long as
the report or other document is not a press release, is not required to be and
has not been distributed to the registrants security holders, and, if
discussing a material event, has already been the subject of a Form 6-K
submission or other Commission filing on EDGAR.
Indicate by check mark whether by furnishing the information contained in this
Form, the registrant is also thereby furnishing the information to the
Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of
1934.
If Yes is marked, indicate below the file number assigned to the registrant
in connection with Rule 12g3-2(b): 82 -
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210, 1167 Kensington Cr. N.W.
Calgary, Alberta
Canada T2N 1X7 |
FOR IMMEDIATE RELEASE
Oncolytics Biotech Inc. Reports REOLYSIN® and Chemotherapeutic Agents are
Synergistic Against NSCL Cancer Cell Lines
CALGARY, AB, November 9, 2006 Oncolytics Biotech Inc. (Oncolytics) (TSX:ONC, NASDAQ:ONCY)
announced today that Dr. Shizuko Sei of SAIC-Frederick, Inc., prime contractor to the National
Cancer Institute at Frederick (NCI-F) in the United States presented a poster at the
18th EORTC-NCI-AACR symposium on Molecular Targets and Cancer Therapeutics today. The
meeting is being held from November 7-10, 2006 in Prague, Czech Republic.
The poster, entitled Synergistic Antitumor Activity of Oncolytic Reovirus and Chemotherapeutic
Agents against Non-small Cell Lung Cancer (NSCLC) covers preclinical work conducted with
collaborators Dr. Joseph E. Tomaszewski of the NCI and Dr. Matt Coffey of Oncolytics Biotech Inc.
under a Clinical Trials Agreement between Oncolytics and NCI.
The research focused on work conducted by the NCI with reovirus in combination with a number of
common chemotherapeutic agents. In general, the combination of reovirus with cisplatin,
gemcitabine, mitomycin or vinblastine was synergistic against NSCLC cell lines sensitive to
anti-cancer drugs. Of particular interest to the researchers, the combination of reovirus and
paclitaxel was uniformly synergistic in all six cell lines examined, including in those with
high-level resistance to paclitaxel or reovirus. The data suggest that the combination of reovirus
and paclitaxel may help in promoting cell-death signaling, resulting in a more efficient and
synergistic anti-cancer effect against these cell lines than using each agent on its own.
Data from the NCI and other investigators examining various co-therapies with REOLYSIN®
is providing Oncolytics with the rationale for its planned combination clinical trial program,
said Dr. Brad Thompson, President and CEO of Oncolytics. This research suggests that
REOLYSIN® can be combined with many existing therapies that are currently broadly used
in the treatment of cancer patients.
The poster will be available on the Oncolytics website following the presentation.
About Oncolytics Biotech Inc.
Oncolytics is a Calgary-based biotechnology company focused on the development of oncolytic viruses
as potential cancer therapeutics. Oncolytics clinical program includes a variety of Phase I and
Phase I/II human trials using REOLYSIN®, its proprietary formulation of the human
reovirus, alone and in combination with radiation. For further information about Oncolytics,
please visit www.oncolyticsbiotech.com
This press release contains forward-looking statements, within the meaning of Section 21E of
the Securities Exchange Act of 1934, as amended. Forward-looking statements, including the
implication of the materials presented at this symposium with respect to REOLYSIN®, the
Companys expectations related to the results of trials investigating delivery of
REOLYSIN®, and the Companys belief as to the potential of REOLYSIN® as a
cancer therapeutic, involve known and unknown risks and uncertainties, which could cause the
Companys actual results to differ materially from those in the forward-looking statements. Such
risks and uncertainties include, among others, accuracy of interpretation of data, the availability
of funds and resources to pursue research and development projects, the efficacy of
REOLYSIN® as a cancer treatment, the success and timely completion of clinical studies
and trials, the Companys ability to successfully commercialize REOLYSIN®, uncertainties
related to the research and development of pharmaceuticals and uncertainties related to the
regulatory process. Investors should consult the Companys quarterly and annual filings with the
Canadian and U.S. securities commissions for additional information on risks and uncertainties
relating to the forward looking statements. Investors are cautioned against placing undue reliance
on forward-looking statements. The Company does not undertake to update these forward-looking
statements.
FOR FURTHER INFORMATION PLEASE CONTACT:
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For Canada:
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For Canada:
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For United States: |
Oncolytics Biotech Inc.
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The Equicom Group
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The Investor Relations Group |
Cathy Ward
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Nick Hurst
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Damian McIntosh |
210, 1167 Kensington Cr NW
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20 Toronto Street
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11 Stone St, 3rd Floor |
Calgary, Alberta T2N 1X7
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Toronto, Ontario M5C 2B8
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New York, NY 10004 |
Tel: 403.670.7377
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Tel: 403.538.4845
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Tel: 212.825.3210 |
Fax: 403.283.0858
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Fax: 403.266.2453
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Fax: 212.825.3229 |
cathy.ward@oncolytics.ca
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nhurst@equicomgroup.com
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dmcintosh@investorrelationsgroup.com |
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