UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 13F Form 13F COVER PAGE Report for the Calendar Year or Quarter Ended: September 30, 2010 Check here if Amendment [ ]; Amendment Number: This Amendment (Check only one.): [ ] is a restatement. [ ] adds new holdings entries. Institutional Investment Manager Filing this Report: Name: GLG Partners, Inc. Address: 390 Park Avenue, 20th Floor New York, NY 10022 13F File Number: 028-13068 The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form. Person Signing this Report on Behalf of Reporting Manager: Name: Alejandro San Miguel Title: General Counsel and Corporate Secretary Phone: 212-224-7200 Signature, Place, and Date of Signing: /s/ Alejandro San Miguel New York, NY November 15, 2010 CERTAIN SECTION 13(F) SECURITIES HAVE BEEN OMITTED FROM THIS REPORT BECAUSE THOSE SECURITIES ARE PART OF THE LEHMAN BANKRUPTCY AND THEREFORE THE INSTITUTIONAL INVESTMENT MANAGER FILING THIS FORM 13F (GLG) DOES NOT HAVE INVESTMENT DISCRETION OVER THOSE SECURITIES. Report Type (Check only one.): [ ] 13F HOLDINGS REPORT. [ ] 13F NOTICE. [ X] 13F COMBINATION REPORT. List of Other Managers Reporting for this Manager: Form 13F File Number Name 028-01190 Russell Investment Company FORM 13F SUMMARY PAGE Report Summary: Number of Other Included Managers: 2 Form 13F Information Table Entry Total: 714 Form 13F Information Table Value Total: $3,805,834 (thousands) List of Other Included Managers: Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional managers with respect to which this report is filed, other than the manager filing this report. No. 13F File Number Name 01 028-10979 GLG Partners LP 02 028-13070 GLG Inc. FORM 13F INFORMATION TABLE VALUE SHARES/ SH/ PUT/ INVSTMT OTHER VOTING AUTHORITY NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DSCRETN MANAGERS SOLE SHARED NONE ------------------------------ ---------------- --------- -------- -------- --- ---- ------- ------------ -------- -------- -------- 3M CO COM 88579Y101 7067 81497 SHR DEFINED 01 02 81497 0 0 ACCENTURE PLC IRELAND SHS CLASS A G1151C101 2842 66889 SHR DEFINED 01 02 66889 0 0 ACE LTD SHS H0023R105 2539 43581 SHR DEFINED 01 02 43581 0 0 ACME PACKET INC COM 004764106 2238 59000 SHR DEFINED 01 59000 0 0 ADOBE SYS INC COM 00724F101 777 29719 SHR DEFINED 01 02 29719 0 0 ADTRAN INC COM 00738A106 1920 54400 SHR DEFINED 01 02 54400 0 0 ADVANCE AUTO PARTS INC COM 00751Y106 2602 44344 SHR DEFINED 01 02 44344 0 0 AERCAP HOLDINGS NV SHS N00985106 1358 114792 SHR DEFINED 01 114792 0 0 AERCAP HOLDINGS NV SHS N00985106 7228 610972 SHR DEFINED 01 02 610972 0 0 AES CORP COM 00130H105 2291 201851 SHR DEFINED 01 02 201851 0 0 AETNA INC NEW COM 00817Y108 4286 135602 SHR DEFINED 01 02 135602 0 0 AFFORDABLE RESIDENTIAL CMNTY NOTE 7.500% 8/1 00828UAB9 9159 8775000 PRN DEFINED 01 8775000 0 0 AFLAC INC COM 001055102 2402 46457 SHR DEFINED 01 02 46457 0 0 AIR PRODS & CHEMS INC COM 009158106 1848 22319 SHR DEFINED 01 02 22319 0 0 AIRCASTLE LTD COM G0129K104 1215 143275 SHR DEFINED 01 143275 0 0 AIRCASTLE LTD COM G0129K104 3415 402697 SHR DEFINED 01 02 402697 0 0 AIRGAS INC COM 009363102 12004 176666 SHR DEFINED 01 176666 0 0 AIRGAS INC COM 009363102 24009 353334 SHR DEFINED 01 02 353334 0 0 AIRGAS INC COM 009363102 6795 100000 SHR CALL DEFINED 01 100000 0 0 AIRGAS INC COM 009363102 13590 200000 SHR CALL DEFINED 01 02 200000 0 0 AK STL HLDG CORP COM 001547108 3584 259503 SHR DEFINED 01 02 259503 0 0 AKAMAI TECHNOLOGIES INC COM 00971T101 4605 91767 SHR DEFINED 01 02 91767 0 0 ALBEMARLE CORP COM 012653101 2298 49097 SHR DEFINED 01 02 49097 0 0 ALCOA INC COM 013817101 3638 300419 SHR DEFINED 01 02 300419 0 0 ALCOA INC COM 013817101 6297 520000 SHR CALL DEFINED 01 02 520000 0 0 ALCON INC COM SHS H01301102 22037 132122 SHR DEFINED 01 132122 0 0 ALCON INC COM SHS H01301102 44330 265784 SHR DEFINED 01 02 265784 0 0 ALIGN TECHNOLOGY INC COM 016255101 2206 112644 SHR DEFINED 01 02 112644 0 0 ALLEGHENY ENERGY INC COM 017361106 539 21975 SHR DEFINED 01 02 21975 0 0 ALLEGHENY TECHNOLOGIES INC COM 01741R102 1858 40000 SHR DEFINED 01 02 40000 0 0 ALLEGHENY TECHNOLOGIES INC NOTE 4.250% 6/0 01741RAD4 22263 16385000 PRN DEFINED 01 16385000 0 0 ALLERGAN INC COM 018490102 6507 97800 SHR CALL DEFINED 01 97800 0 0 ALLERGAN INC COM 018490102 2649 39814 SHR DEFINED 01 02 39814 0 0 ALLIANT ENERGY CORP COM 018802108 490 13488 SHR DEFINED 01 02 13488 0 0 ALLSTATE CORP COM 020002101 3338 105790 SHR DEFINED 01 02 105790 0 0 ALLSTATE CORP COM 020002101 286 9058 SHR DEFINED 01 9058 0 0 ALPHA NATURAL RESOURCES INC COM 02076X102 1205 29272 SHR DEFINED 01 02 29272 0 0 ALUMINA LTD SPONSORED ADR 022205108 1046 149393 SHR DEFINED 01 02 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COM 055921100 4048 100000 SHR CALL DEFINED 01 02 100000 0 0 BOEING CO COM 097023105 2820 42377 SHR DEFINED 01 02 42377 0 0 BOSTON PPTYS LTD PARTNERSHIP NOTE 3.750% 5/1 10112RAG9 5531 5000000 PRN DEFINED 01 5000000 0 0 BOSTON SCIENTIFIC CORP COM 101137107 1165 190080 SHR DEFINED 01 02 190080 0 0 BP PLC SPONSORED ADR 055622104 1511 36700 SHR DEFINED 01 02 36700 0 0 BRE PROPERTIES INC NOTE 4.125% 8/1 05564EBH8 4332 4165000 PRN DEFINED 01 4165000 0 0 BRISTOL MYERS SQUIBB CO COM 110122108 3207 118310 SHR DEFINED 01 02 118310 0 0 BROADCOM CORP CL A 111320107 13570 383443 SHR DEFINED 01 383443 0 0 BROADCOM CORP CL A 111320107 1951 55118 SHR DEFINED 01 02 55118 0 0 BROADCOM CORP CL A 111320107 4128 116653 SHR DEFINED 02 116653 0 0 BROADSOFT INC COM 11133B409 1968 227251 SHR DEFINED 01 02 227251 0 0 C H ROBINSON WORLDWIDE INC COM NEW 12541W209 1522 21761 SHR DEFINED 01 02 21761 0 0 CABLEVISION SYS CORP CL A NY CABLVS 12686C109 1351 51582 SHR DEFINED 01 51582 0 0 CABLEVISION SYS CORP CL A NY 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SOLAR LIMITED SPON ADR 89628E104 3106 102923 SHR DEFINED 01 02 102923 0 0 TYCO INTERNATIONAL LTD SHS H89128104 4428 120547 SHR DEFINED 01 02 120547 0 0 UAL CORP NOTE 4.500% 6/3 902549AH7 17719 17500000 PRN DEFINED 01 17500000 0 0 UAL CORP NOTE 6.000%10/1 902549AJ3 14369 5000000 PRN DEFINED 01 5000000 0 0 ULTRA PETROLEUM CORP COM 903914109 1918 45685 SHR DEFINED 01 02 45685 0 0 UNION PAC CORP COM 907818108 5061 61874 SHR DEFINED 01 02 61874 0 0 UNITED DOMINION REALTY TR IN NOTE 4.000%12/1 910197AK8 2531 2500000 PRN DEFINED 01 2500000 0 0 UNITED PARCEL SERVICE INC CL B 911312106 2558 38364 SHR DEFINED 02 38364 0 0 UNITED PARCEL SERVICE INC CL B 911312106 1996 29925 SHR DEFINED 01 29925 0 0 UNITED PARCEL SERVICE INC CL B 911312106 10806 162026 SHR DEFINED 01 02 162026 0 0 UNITED STATES STL CORP NEW COM 912909108 570 13000 SHR DEFINED 01 02 13000 0 0 UNITED TECHNOLOGIES CORP COM 913017109 6825 95818 SHR DEFINED 01 02 95818 0 0 UNITED THERAPEUTICS CORP DEL COM 91307C102 2520 45000 SHR 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