Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Silva Francisco
   2. Issuer Name and Ticker or Trading Symbol
BioRestorative Therapies, Inc. [BRTX] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
VP of Research and Development
(Last)
(First)
(Middle)
40 MARCUS DRIVE		 3. Date of Earliest Transaction (Month/Day/Year)
03/25/2019
(Street)

MELVILLE, NY 11747		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock               170 I IRA
Common Stock               4,075 D  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option $ 4.7 03/25/2019   D     4,000   (1) 04/04/2021 Common Stock 4,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   4,000     (1) 04/04/2021 Common Stock 4,000 (12) 4,000 D  
Stock Option $ 4.7 03/25/2019   D     150 06/24/2011 06/23/2021 Common Stock 150 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   150   06/24/2011 06/23/2021 Common Stock 150 (12) 150 D  
Stock Option $ 4.7 03/25/2019   D     1,000 11/16/2011 11/15/2021 Common Stock 1,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   1,000   11/16/2011 11/15/2021 Common Stock 1,000 (12) 1,000 D  
Stock Option $ 4.7 03/25/2019   D     2,000   (2) 02/09/2022 Common Stock 2,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   2,000     (2) 02/09/2022 Common Stock 2,000 (12) 2,000 D  
Stock Option $ 4.7 03/25/2019   D     5,500   (3) 05/02/2022 Common Stock 5,500 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   5,500     (3) 05/02/2022 Common Stock 5,500 (12) 5,500 D  
Stock Option $ 4.7 03/25/2019   D     4,000   (4) 12/07/2022 Common Stock 4,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   4,000     (4) 12/07/2022 Common Stock 4,000 (12) 4,000 D  
Stock Option $ 4.7 03/25/2019   D     5,000   (5) 10/04/2023 Common Stock 5,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   5,000     (5) 10/04/2023 Common Stock 5,000 (12) 5,000 D  
Stock Option $ 4.7 03/25/2019   D     12,500   (6) 02/18/2024 Common Stock 12,500 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   12,500     (6) 02/18/2024 Common Stock 12,500 (12) 12,500 D  
Stock Option $ 4.7 03/25/2019   D     2,000 03/12/2014 03/11/2024 Common Stock 2,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   2,000   03/12/2014 03/11/2024 Common Stock 2,000 (12) 2,000 D  
Stock Option $ 4.7 03/25/2019   D     2,000 04/14/2014 05/02/2022 Common Stock 2,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   2,000   04/14/2014 05/02/2022 Common Stock 2,000 (12) 2,000 D  
Stock Option $ 4.7 03/25/2019   D     37,500   (7) 10/23/2024 Common Stock 37,500 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   37,500     (7) 10/23/2024 Common Stock 37,500 (12) 37,500 D  
Stock Option $ 4.7 03/25/2019   D     25,000   (8) 09/04/2025 Common Stock 25,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   25,000     (8) 09/04/2025 Common Stock 25,000 (12) 25,000 D  
Stock Option $ 3.73 03/25/2019   D     60,000   (9) 06/10/2026 Common Stock 60,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   60,000     (9) 06/10/2026 Common Stock 60,000 (12) 60,000 D  
Stock Option $ 2.8 03/25/2019   D     80,000   (10) 07/12/2027 Common Stock 80,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   80,000     (10) 07/12/2027 Common Stock 80,000 (12) 80,000 D  
Stock Option $ 1.23 03/25/2019   D     100,000   (11) 10/29/2028 Common Stock 100,000 (12) 0 D  
Stock Option $ 0.75 03/25/2019   A   100,000     (11) 10/29/2028 Common Stock 100,000 (12) 100,000 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Silva Francisco
40 MARCUS DRIVE
MELVILLE, NY 11747		       VP of Research and Development  

Signatures

 /s/ Francisco Silva   03/25/2019
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The option is exercisable to the extent of 2,000 shares on each of April 5, 2011 and April 5, 2012.
(2) The option is exercisable to the extent of 1,000 shares on each of February 10, 2012 and February 10, 2013.
(3) The option is exercisable to the extent of 500 shares on each of May 3, 2013, May 3, 2014 and May 3, 2015, became exercisable to the extent of 1,000 shares based on the satisfaction of certain conditions and is exercisable to the extent of 3,000 shares subject to the satisfaction of certain conditions.
(4) The option is exercisable to the extent of 2,000 shares on each of December 7, 2012 and December 7, 2013.
(5) The option is exercisable to the extent of 2,500 shares on each of October 4, 2013 and October 4, 2014.
(6) The option is exercisable to the extent of 4,167 shares on each of February 18, 2014 and February 18, 2015, and 4,166 shares on February 18, 2016.
(7) The option is exercisable to the extent of 12,500 shares on each of October 23, 2015, October 23, 2016 and October 23, 2017.
(8) The option is exercisable to the extent of 8,334 shares on September 4, 2016 and 8,333 shares on each of September 4, 2017 and September 4, 2018.
(9) The option is exercisable to the extent of 20,000 shares on each of June 10, 2017, June 10, 2018 and June 10, 2019.
(10) The option is exercisable to the extent of 26,667 shares on each of July 12, 2018 and July 12, 2019, and 26,666 shares on July 12, 2020.
(11) The option is exercisable to the extent of 33,334 shares on October 29, 2019, and 33,333 shares on each of October 29, 2020 and October 29, 2021.
(12) The reported transactions involved an amendment of an outstanding stock option, resulting in the deemed cancellation of the "old" stock option and the grant of a "replacement" stock option at a reduced exercise price.

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