The most recent short interest data has been released for the 12/29/2017 settlement date, which shows a 445,280 share increase in total short interest for Loxo Oncology, Inc (LOXO), to 4,463,652, an increase of 11.08% since 12/15/2017. Total short interest is just one way to look at short data; another metric that we here at Dividend Channel find particularly useful is the "days to cover" metric because it considers both the total shares short and the average daily volume of shares traded..