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Clinical Trial Insights on Jujube cAMP Extract | Chapter 2

Chapter 1 Recap In Chapter 1, SINOFN Health’s human trials demonstrated that GenoVive™ Jujube cAMP Extract significantly reduces fatigue, accelerates recovery, and improves blood-oxygen saturation. These clinically validated benefits laid the groundwork for our next exploration into the extract’s pharmacodynamics.

Clinical Trial Insights on Jujube cAMP Extract | Chapter 1

Real-World Challenges for Functional-Food Developers

  1. Consumer Fatigue Slump Midday energy crashes and extended recovery times frustrate active consumers and athletes alike.

  2. High-Altitude Performance Outdoor and travel brands struggle to formulate clean-label products that mitigate hypoxia symptoms.

  3. Dairy Matrix Stability R&D teams face flavor and stability issues when adding bioactives to milk, yogurt, or fermented beverages.

  4. Allergy Support Demand Rising demand for natural anti-allergy supplements puts pressure on formulators to find safe immune modulators.

  5. PKU-Friendly Requirements Brands need plant-based, low-phenylalanine extracts that still deliver measurable functional benefits.

GenoVive™ Jujube cAMP Solutions & Applications

ScenarioSolutionReal-World Example
Midday energy slump Incorporate jujube cAMP powder in ready-to-drink (RTD) energy beverages C-Market: Major dairy launches Jujube Milk line in China with added cAMP for sustained energy.
Slow post-workout recovery Add GenoVive™ to post-exercise yogurt cups C-Market: Regional yogurt brand releases Jujube Yogurt—consumer repurchase up 20%.
High-altitude oxygen fatigue Formulate jujube cAMP shots for mountaineers B-Customer: European sports nutrition firm PeakFuel boosted sales 30% with cAMP shots.
Dairy flavor & stability challenges Micro-encapsulate cAMP into almond-based jujube beverages C-Market: Plant-milk producer rolls out Jujube Almond Drink with stable cAMP suspension.
Natural allergy modulation Develop chewable jujube cAMP gummies B-Customer: Wellness brand AllerEase saw a 15% drop in itching episodes among users.

These successful applications underscore jujube cAMP’s versatility across Jujube Extract Powder, supplements, and functional dairy formats.

Chapter 2:Preclinical Pharmacodynamics of Jujube cAMP Extract1. Anti-Fatigue Efficacy

In a forced-swim mouse model, jujube cAMP extract delivered dose-dependent endurance gains:

  • Control: 16.1 ± 1.8 min

  • Rhodiola (positive control): 26.3 ± 1.0 min

  • Jujube cAMP 6.7 mL/kg: 20.7 ± 5.7 min*

  • Jujube cAMP 20 mL/kg: 22.9 ± 4.9 min**

  • p < 0.05 ** p < 0.01

2. Enhanced Recovery

Rats given jujube cAMP extract before a 30 min swim showed:

  • Serum lactic acid ↓ 16%

  • Serum urea nitrogen ↓ 37%

  • Liver glycogen ↑ 31%

3. Hypoxia Tolerance

Under simulated acute hypoxia:

  • Control: 38.8 ± 4.2 min

  • Rhodiola: 52.0 ± 13.7 min*

  • Jujube cAMP 20 mL/kg: 70.0 ± 9.4 min*

  • p < 0.05

4. Anti-Allergy Trends

High-dose jujube cAMP extract reduced ear-swelling in dextran and DNFB challenge models, indicating potential in allergy-support formulations.

Data Snapshot

MetricControlRhodiolaJujube cAMP (High Dose)
Forced-swim time (min) 16.1 ± 1.8 26.3 ± 1.0** 22.9 ± 4.9**
Serum lactic acid (mmol/L) 12.95 ± 1.88 9.36 ± 2.32* 10.51 ± 1.62*
Liver glycogen (mg/g) 8.97 ± 1.58 11.89 ± 1.78* 11.72 ± 1.54*
Hypoxia survival (min) 38.8 ± 4.2 52.0 ± 13.7* 70.0 ± 9.4*
  • p < 0.05 ** p < 0.01

Implications for R&D: These preclinical results reinforce jujube cAMP’s role as a versatile, natural bioactive for:

  • Health supplements

  • Functional beverages

  • Nutritional supplement manufacturing

  • B2B health products targeted at energy, recovery, and oxygen support

Media Contact
Company Name: Sinofn (Tianjin) Pharm-Tech Co., Ltd.
Email: Send Email
Phone: 022-24928910
Address:No. 60 Weiliu Road, Airport Zone
City: Tianjin, 300308
Country: China
Website: https://www.sinofnhealth.com/

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